At Davos, Stephen Pagliuca, American private equity investor and longtime attendee, sat down with Josh Kampel of Worth Media Group to reflect on the evolution of the conference and discuss his latest ventures in biotech innovation, AI-driven therapeutics, and community impact through sports.

Having attended Davos for 18 years, Pagliuca noted its transformation from a small academic forum into a global stage where world leaders and industry executives convene to shape the future. Now, after stepping back from Bain Capital, he has shifted his focus to building lasting institutions through his family office.

A key highlight of his work is Harvard’s Life Lab, a state-of-the-art biotech incubator that has already launched 60 biotech companies and raised $500 million in capital. Inspired by its success, Pagliuca is spearheading Arena BioWorks, a new initiative designed to accelerate therapeutic development using AI and cutting-edge biotech innovations. Structured like a venture capital firm, Arena BioWorks allows scientists to collaborate and participate in company spinouts, fostering a dynamic ecosystem for medical breakthroughs.

Beyond biotech, Pagliuca discussed his ownership of the Boston Celtics and his commitment to leveraging sports for social good. Through the Boston Shamrock Foundation and initiatives like Boston Celtics for Social Justice, he is driving meaningful change in areas such as racial equity and healthcare access. He emphasized the unique power of sports to unite communities and create lasting societal impact.

From biotech to basketball, Pagliuca continues to shape industries and communities, demonstrating how business, technology, and sports can intersect to drive innovation and social progress.